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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACTR3 All Species: 43.33
Human Site: S350 Identified Species: 63.56
UniProt: P61158 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P61158 NP_005712.1 418 47371 S350 V D A R L K L S E E L S G G R
Chimpanzee Pan troglodytes XP_001143822 413 46798 A345 D L K R V V D A R L R L S E E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_853309 565 63553 S497 V D A R L K L S E E L S G G R
Cat Felis silvestris
Mouse Mus musculus Q99JY9 418 47339 S350 V D A R L K L S E E L S G G R
Rat Rattus norvegicus XP_342612 418 47616 S350 V D A R L K L S Q E L S G G R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513007 482 55165 S414 V D A R L K L S E E L S G G R
Chicken Gallus gallus Q90WD0 418 47403 S350 V D A R L K L S E E L S G G R
Frog Xenopus laevis P10995 377 41970 G304 A N N V L S G G T T M Y P G I
Zebra Danio Brachydanio rerio NP_001003944 418 47376 S350 V D A R L K L S E E L S G G K
Tiger Blowfish Takifugu rubipres O73723 418 47447 S350 V D A R L K M S E E L S G G K
Fruit Fly Dros. melanogaster P32392 418 47014 S350 V D T R L R I S E N L S E G R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9N4I0 425 48069 S357 S D G R L Q M S E T L S G G R
Sea Urchin Strong. purpuratus XP_780265 418 47124 S350 V D N R L K L S E Q L S G G K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SAF1 427 47641 N359 V D A R V L A N N A R T G G E
Baker's Yeast Sacchar. cerevisiae P47117 449 49523 A382 S I V N N R I A Q S E L L S G
Red Bread Mold Neurospora crassa P78712 439 47833 A369 L V D T R I K A S E V R S G G
Conservation
Percent
Protein Identity: 100 84.6 N.A. 73.6 N.A. 99.7 91.1 N.A. 78.2 98.5 37.3 97.3 96.6 80.6 N.A. 76 84.6
Protein Similarity: 100 91.8 N.A. 73.8 N.A. 100 96.4 N.A. 83.4 99.7 52.6 99.2 99.5 90.6 N.A. 85.1 92.5
P-Site Identity: 100 6.6 N.A. 100 N.A. 100 93.3 N.A. 100 100 13.3 93.3 86.6 66.6 N.A. 66.6 80
P-Site Similarity: 100 20 N.A. 100 N.A. 100 100 N.A. 100 100 26.6 100 100 80 N.A. 80 93.3
Percent
Protein Identity: N.A. N.A. N.A. 58.7 59.2 61
Protein Similarity: N.A. N.A. N.A. 74.9 69.2 72.4
P-Site Identity: N.A. N.A. N.A. 40 0 13.3
P-Site Similarity: N.A. N.A. N.A. 60 26.6 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 57 0 0 0 7 19 0 7 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 75 7 0 0 0 7 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 63 57 7 0 7 7 13 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 7 0 0 0 7 7 0 0 0 0 69 88 13 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 0 0 7 13 0 0 0 0 0 0 0 7 % I
% Lys: 0 0 7 0 0 57 7 0 0 0 0 0 0 0 19 % K
% Leu: 7 7 0 0 75 7 50 0 0 7 69 13 7 0 0 % L
% Met: 0 0 0 0 0 0 13 0 0 0 7 0 0 0 0 % M
% Asn: 0 7 13 7 7 0 0 7 7 7 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % P
% Gln: 0 0 0 0 0 7 0 0 13 7 0 0 0 0 0 % Q
% Arg: 0 0 0 82 7 13 0 0 7 0 13 7 0 0 50 % R
% Ser: 13 0 0 0 0 7 0 69 7 7 0 69 13 7 0 % S
% Thr: 0 0 7 7 0 0 0 0 7 13 0 7 0 0 0 % T
% Val: 69 7 7 7 13 7 0 0 0 0 7 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _